It’s easy to not fall into dependence if you have self restraint. I put immense effort into research, to make sure my doses are safe, infrequent enough per drug, and I’m doing it for a good reason (enjoyment is a reason, as long as I have other hobbies). I hope to one day be a major advocate in drug safety, and create guidelines for responsible use. It’s no different than drinking safely, but with different things.