Probably unpopular, but I really like Studio One. Reaper is more powerful, and I love it too, but there's something about Studio One that just let me wrap my brain around it the first time I used it. For me, it's great for quick and dirty production which is a lot of what I do and "just works" with my interface and mixing console.

Of course that's not the case for everyone and a lot of folks want and need something with more to it.