There is a possibility that the Higgs field isn’t at it’s lowest energy state, and that a random quantum tunneling event could drag the Higgs field to that lower state. In this unsettling scenario, a bubble pops into existence somewhere in the universe. Inside the bubble, the laws of physics are wildly different than they are outside the bubble. The bubble expands at the speed of light, eventually taking over the entire universe. Galaxies drift apart, atoms can’t hold themselves together, and the ways that particles interact are fundamentally changed. Whatever form the universe takes after this event certainly wouldn’t be hospitable for humans.
We have no way to know what the resultant physics would be like within the bubble, so there is no way to even speculate about what would happen.